Research Article
Shikonin Inhibits Der p 2-Induced Cytokine and Chemokine Expression in Dendritic Cells in Patients with Atopic Dermatitis
Table 4
Proinflammatory cytokine levels of the Der p 2 group and shikonin-treated group (n = 6).
| | Der p 2 | Shikonin | value | | Mean | SD | Mean | SD |
| | IL-4 | 0.5 | ±0.4 | 0.3 | ±0.4 | 0.138 | | IL-5 | 0.7 | ±1.7 | 0.9 | ±1.1 | 0.715 | | IL-6 | 3.3 | ±4.1 | 0.7 | ±0.7 | 0.043 | | IL-9 | 21.6 | ±22.6 | 5.3 | ±5.3 | 0.028 | | IL-13 | 1.3 | ±2.2 | 1.2 | ±1.5 | 0.893 | | IL-17A | 12.1 | ±9.6 | 5.5 | ±2.6 | 0.027 | | MCP-1 | 91.0 | ±112.9 | 15.6 | ±14.5 | 0.028 | | MIP-1α | 330.6 | ±505.5 | 9.9 | ±6.7 | 0.046 | | MIP-1β | 610.2 | ±919.4 | 6.9 | ±7.2 | 0.028 | | RANTES | 29.8 | ±36.4 | 3.6 | ±2.0 | 0.028 |
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Data are expressed as the mean ± standard deviation (SD). Data were analyzed using the Wilcoxon signed-rank test.
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