Research Article
Integrating Pharmacology and Microbial Network Analysis with Experimental Validation to Reveal the Mechanism of Composite Sophora Colon-Soluble Capsule against Ulcerative Colitis
Figure 7
Effect of treatment on the microbiome of DSS-induced colitis. (a-b) Cooccurrence network of gut microbiome, on the 14th day, in association with multiple groups and CSCC group. (c) Abundance and percentage of the different bacterial families in each group. The most abundant family was Lactobacillaceae in the mice that received CSCC enema treatment. (d) Differences in abundance of Lactobacillaceae, Verrucomicrobiaceae, and Ruminococcaceae (family levels), L. reuteri, L. johnsonii, and Akkermansia (species levels) in different groups. Data are expressed as means ± standard deviation (n = 6). , vs. DSS group. (e) The relative populations of Verrucomicrobiaceae and Ruminococcaceae in the CSCC group at multiple time points.
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