Ultrastructural Changes in Hepatocytes and Chemopreventive Effects of Short-Term Administration of Curcuma longa L. against Oxidative Stress-Induced Toxicity: Improvement Mechanisms of Liver Detoxification

Table 1

Lesion scoring for tissues after CL supplementation for six consecutive days.

Organ	Lesion	Control		1^st day	3^rd day	5^th day	6^th day
		NCx	PCx
Liver	Congestion	0.00	0.00	0.00	0.03 ± 0.01	0.04 ± 0.01	0.05 ± 0.006
	Dilation of sinusoid	0.00	0.00	0.00	0.01 ± 0.006	0.01 ± 0.006	0.02 ± 0.01
	Inflammatory cell infiltration	0.00	0.00	0.00	0.00	0.01 ± 0.006	0.01 ± 0.013
	Hepatocellular degeneration	0.00	0.00	0.00	0.00	0.00	0.00
	Hepatocellular necrosis	0.00	0.00	0.00	0.00	0.00	0.00
Kidney	Congestion	0.00	0.00	0.00	0.00	0.01 ± 0.006	0.02 ± 0.011
	Interstitial leukocytic infiltration	0.00	0.00	0.00	0.00	0.00	0.00
Spleen	Congestion	0.00	0.00	0.00	0.00	0.01 ± 0.006	0.01 ± 0.006
	Lymphoid depletion SWP	0.00	0.00	0.00	0.00	0.00	0.00
	Mononuclear infiltration SRP	0.00	0.00	0.00	0.00	0.00	0.00
	Total lesion score	0.00	0.00	0.00	0.04	0.08	0.11