Research Article

Extract of Pogostemon cablin Possesses Potent Anticancer Activity against Colorectal Cancer Cells In Vitro and In Vivo

Figure 6

PCa suppressed tumor growth via induction of cell apoptosis in vivo. Mice were subcutaneously implanted with CT26 cells and treated (s.c.) with 200 mg/kg PCa once every two days for 40 days. Tumor volume (a), survival (b), and body weight (c) were recorded once every two days, and mice were sacrificed when the volume of the tumor exceeded 1500 mm3. Results are expressed as mean ± SD. versus the vehicle group. (d) Cell apoptosis was determined through tissue TUNEL assays. (e) HE staining of the organs, including liver, kidney, and intestine, was used for assessing toxicity.