Research Article

Evaluation of Subchronic Toxicity and Genotoxicity of Ethanolic Extract of Aster glehni Leaves and Stems

Table 5

Histopathologic findings of male and female SD rats in the 13-week repeated oral toxicity study of EAG.

OrgansFindingsEAG (mg/kg/day)
MaleFemale
01,2502,5005,00001,2502,5005,000

Nonglandular stomachHyperplasia, squamous cells, limiting ridge037100138
No. of animals examined1010101010101010

/Significant difference at / levels compared with the negative control by Fisher two-tailed test.