The Aqueous Extract of Eucommia Leaves Promotes Proliferation, Differentiation, and Mineralization of Osteoblast-Like MC3T3-E1 Cells

Table 5

List of DEGs negatively regulating the proliferation of osteoblasts (ELAE vs. Blank).

Gene name	Blank (FPKM)	ELAE (FPKM)	log2 fold change (ELAE/Blank)	p value
Nucleophosmin 1 (Npm1)	573.81	191.57	−1.58	0
Eukaryotic translation initiation factor 3, subunit E (Eif3e)	160.26	76.59	−1.07	4.43E − 85
Chromobox 3 (Cbx3)	86.54	42.39	−1.03	1.25E − 53
Proteasome (prosome, macropain) 26S subunit, ATPase, 6 (Psmc6)	47.95	14.09	−1.77	6.88E − 57
Fibroblast growth factor 7 (Fgf7)	44.90	20.09	−1.16	1.73E − 50
Fragile X mental retardation gene 1, autosomal homolog (Fxr1)	33.40	10.21	−1.71	1.17E − 52
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x)	33.06	8.20	−2.01	3.67E − 143
Muscleblind-like 1 (Drosophila) (Mbnl1)	32.34	12.31	−1.40	9.26E − 86
Cell division cycle 27 (Cdc27)	8.92	2.33	−1.94	1.95E − 48