Zanthoxylum zanthoxyloides Alkaloidal Extract Improves CCl₄-Induced Hepatocellular Carcinoma-Like Phenotypes in Rats

Table 3

Effect of ZZAE on body weight changes.

Treatment groups	Initial mean body weight (g)	Final mean body weight (g)	Change in mean body weight (g)	% change in mean body weight
Control	182.851 ± 10.39	274.448 ± 9.125	91.60 ± 9.002	50.1
Model	196.074 ± 7.245	224.990 ± 4.093	28.92 ± 8.357^#	14.74
Carvedilol	174.803 ± 5.39	227.275 ± 3.224	52.472 ± 4.624	30.01
^aTween20	177.005 ± 3.689	209.336 ± 4.579	32.331 ± 6.353	18.26
ZZAE (mg/kg)
50	182.446 ± 7.576	239.648 ± 6.397	57.202 ± 7.788	31.35
100	177.121 ± 3.58	242.089 ± 9.771	64.968 ± 9.753	36.68
200	184.874 ± 3.331	233.421 ± 4.243	48.547 ± 3.24	26.26

(control versus model groups); (model versus all other treatment groups); ^a(vehicle, 1 mL/rat, once daily).