Methanolic Extract of Myrsine africana Leaf Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Albino Mice

Table 3

Hypoglycemic activity of the methanolic extract of M. africana leaf in normoglycemic mice.

Group	Fasting blood glucose level (mg/dl)
	0 hr	1 hr	2 hr	4 hr	6 hr
NS 10 ml/kg	89.1 ± 5.1	90.1 ± 4	83.6 ± 5.7	93.3 ± 4.9	84.3 ± 6.3
MA 250 mg/kg	86.6 ± 3.3	90.6 ± 6.4	85.1 ± 6.3	94.6 ± 5.7	85.8 ± 6.4
MA 500 mg/kg	85.8 ± 5.5	88.5 ± 3.3	87.1 ± 5.3	88.6 ± 5.7	87 ± 6
MA 1000 mg/kg	89.1 ± 5.9	90.8 ± 6.1	87.3 ± 6.3	92.3 ± 3.8	85.3 ± 6.9
GLC 5 mg/kg	89.8 ± 3.7	81.1 ± 3.3^aE bE dE^βF	68.8 ± 4.1^aF bG cG dG^βG	67.6 ± 3.38^aG bG cG dG^βG	57.1 ± 3.7^aG bG cG dG^βG

Values are expressed as mean ± SD; n = 6; ^a compared with the negative control, ^b compared with MA 250 mg/kg, ^c compared with MA 500 mg/kg, ^d compared with MA 1000 mg/kg, and ^β compared with the baseline blood glucose level; ^E, ^F, ^G; MA, Myrsine africana leaf extract; NS, normal saline; GLC, glibenclamide.