Methanolic Extract of Myrsine africana Leaf Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Albino Mice

Table 6

Antihyperglycemic activity of repeated daily dose of M. africana methanolic leaf extract in diabetic mice.

Group	Fasting blood glucose level (mg/dl)
	Baseline	7^th day	14^th day
Diabetic control	262.8 ± 29.7 ^nG	234.1 ± 28.8	226.8 ± 31.9
MA 250 mg/kg	270.1 ± 50.5 ^nG	199.8 ± 42.3 ^βG	172.1 ± 13 ^βG^αF
MA 500 mg/kg	270 ± 39.6 ^nG	179.6 ± 17.4 ^βG^αE	167.6 ± 13.7 ^βG^αG
MA 1000 mg/kg	256.5 ± 48.9 ^nG	167.1 ± 9.3 ^βG^αE	159.3 ± 6.9 ^βG^αG
GLC 5 mg/kg	283.6 ± 50.1 ^nG	165.1 ± 21.3 ^βG^αF	140.5 ± 32.5 ^βG^αG
Normal control	80.6 ± 5.7	61 ± 4.3	66.5 ± 5.3

Values are expressed as mean ± SD; n = 6; ^α compared with diabetic control, ⁿ compared with normal control, ^β compared with baseline blood glucose level; ^E, ^F, ^G; MA, Myrsine africana leaf extract; NS, normal saline; GLC, glibenclamide.