Methanolic Extract of Myrsine africana Leaf Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Albino Mice

Table 8

Effect of the repeated daily dose of M. africana methanolic leaf extract on the serum lipid level in diabetic mice.

Group	Serum lipid level (mg/dl)
	HDL-C	TC	TG
Diabetic control	19.6 ± 2.1 ^nG	177.3 ± 3.3 ^nG	142.8 ± 7.1 ^nG
MA 250 mg/kg	25.5 ± 1.8 ^nG^αE	153.6 ± 2.1 ^nG^αG	135.1 ± 4.4 ^nG
MA 500 mg/kg	26.5 ± 1.8 ^nG^αE	157.5 ± 13 ^nG^αG	133.6 ± 3.5 ^nG^αE
MA 1000 mg/kg	28.8 ± 2.4 ^nG^αG	153 ± 4 ^nG^αG	130.1 ± 2.8 ^nG^αF
GLC 5 mg/kg	36.6 ± 5 ^αG bF cF dF	83 ± 2 ^αG bF cF dF	57.5 ± 4.5 ^αG bF cF dF
Normal control	38.1 ± 3.1	70.3 ± 3.7	53.3 ± 3.7

Values are expressed as mean ± SD; n = 6; ^α compared with diabetic control, ^b compared with MA 250 mg/kg, ^c compared with MA 500 mg/kg, ^d compared with MA 1000 mg/kg, and ⁿ compared with normal control; ^E, ^F, ^G; MA, Myrsine africana leaf extract; GLC, glibenclamide; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol.