Evidence-Based Complementary and Alternative Medicine / 2021 / Article / Tab 5 / Research Article
Analysis of the Efficacy and Pharmacological Mechanisms of Action of Zhenren Yangzang Decoction on Ulcerative Colitis Using Meta-Analysis and Network Pharmacology Table 5 Key target proteins of ZRYZD acting on UC.
Key target Entry Entry name Protein names Degree TP53 P04637 P53_HUMAN Cellular tumor antigen p53 37 VEGFA P15692 VEGFA_HUMAN Vascular endothelial growth factor A 35 JUN P05412 JUN_HUMAN Transcription factor AP-1 35 CASP3 P42574 CASP3_HUMAN Caspase-3 34 ESR1 P03372 ESR1_HUMAN Estrogen receptor 33 PTGS2 P35354 PGH2_HUMAN Prostaglandin G/H synthase 2 30 MMP9 P14780 MMP9_HUMAN Matrix metalloproteinase-9 30 PPARG P37231 PPARG_HUMAN Peroxisome proliferator-activated receptor gamma 28 BCL2L1 Q07817 B2CL1_HUMAN Bcl-2-like protein 1 27 CASP8 Q14790 CASP8_HUMAN Caspase-8 27