Review Article

The Effect of Probiotics in Stroke Treatment

Table 4

Meta-analysis for continuous variables.

Effect indexDetail indexStudies includedHeterogeneity testModelMD (95% CI)

Effect on strokeNIHSS score2 [20, 31]I2 = 93%, Random effects model−1.11 (−7.92, 5.70),
Hospital stay duration5 [17, 21, 23, 24, 29]I2 = 81%, Random effects model−8.94 (−11.39, −6.50),
Bedrest duration3 [17, 24, 29]I2 = 0%, Fixed effects model−10.34 (−11.30, −9.39),

Blood nutrition indicatorsHB7 [12, 16, 21, 25, 26, 30, 31]I2 = 51%, Fixed effects model8.36 (6.34, 10.38),
ALB9 [12, 16, 21, 23, 25, 27, 30, 31]I2 = 54%, Random effects model2.91 (2.45, 3.37),
TP6 [16, 21, 25, 27, 31]I2 = 82%, Random effects model4.90 (2.43, 7.38),
PA4 [12, 16, 27, 31]I2 = 74%, Random effects model15.50 (9.2, 21.79),

Inflammation indicatorsTNF-α3 [14, 21, 26]I2 = 78%, Random effects model−3.22 (−5.61, −0.82),
IL-62 [21, 26]I2 = 0%, Fixed effects model−16.40 (−21.97, −10.83),
IL-102 [14, 23]I2 = 0%, Fixed effects model−6.63 (−12.55, −0.70), P = 0.03
hs-CRP2 [14, 23]I2 = 0%, Fixed effects model−2.82 (−10.10, 4.47),
PCT2 [14, 23]I2 = 0%, Fixed effects model−0.35 (−2.58, 1.89),