Review Article

The Effect of Probiotics in Stroke Treatment

Table 5

Binary variable meta-analysis results.

Effect indexDetail indexStudyHeterogeneity testModelRR (95% CI)

Adverse reactionsVomiting3 [16, 22, 27]I2 = 0%, Fixed effects model0.83 (0.46, 1.51),
Stress ulcer2 [22, 30]I2 = 14%, Fixed effects model0.47 (0.22, 1.02),
Esophageal reflux8 [11, 13, 16, 17, 22, 28, 29, 31]I2 = 29%, Fixed effects model0.43 (0.25, 0.74),
Bloating10 [11, 13, 17, 22, 27, 29, 31, 33]I2 = 0%, Fixed effects model0.39 (0.26, 0.58),
Constipation12 [11, 13, 16, 19, 23, 27, 29, 33]I2 = 0%, Fixed effects model0.31 (0.21, 0.45),
Diarrhea14 [11, 13, 16, 19, 22, 23, 27, 29, 31]I2 = 0%, Fixed effects model0.22 (0.14, 0.34),
Gastric retention4 [11, 13, 2729]I2 = 0%, Fixed effects model0.34 (0.19, 0.60),
Gastrointestinal bleeding10 [13, 15, 17, 19, 25, 26, 28, 29, 31]I2 = 0%, Fixed effects model0.39 (0.28, 0.54),

Complication rateLung infection12 [11, 13, 15, 17, 25, 26, 2832]I2 = 65%, Random effects model0.44 (0.27, 0.72),
Gastrointestinal infection4 [11, 13, 17, 29]I2 = 0%, Fixed effects model0.40 (0.23, 0.68),
Urinary tract infection6 [11, 13, 15, 17, 28, 29]I2 = 0%, Fixed effects model0.27 (0.15, 0.49),

Poor prognostic indicatorsMortality rate4 [16, 17, 22, 29]I2 = 0%, Fixed effects model0.45 (0.22, 0.93),
Bacterial imbalance rate6 [11, 15, 25, 26, 28, 32]I2 = 0%, Fixed effects model0.32 (0.21, 0.48),