Review Article
Chinese Herbal Medicine Alleviates Myocardial Ischemia/Reperfusion Injury by Regulating Endoplasmic Reticulum Stress
Table 2
The role of patented drugs from Chinese herbs in the regulation of ER stress in myocardial I/R.
| Patented drugs | Experimental models | Effects | Mechanisms | References |
| Qishen granule | OGD/R in H9c2 cells | Apoptosis↓, ER stress↓ | Bcl-2/BAX↑, caspases-3/12↓, IRE1-CryAB↑ | [161] | Shuxuening injection | I/R injury in rats | Oxidative damage↓, inflammation↓, ER stress↓ | CK↓, LDH↓, cTnI↓, MDA↓, SOD↑, GSH-Px↑, CAT↑, GRP78↓, CRT↓, CHOP↓, caspase-12↓, TLR4/NF-κB↓ | [162] |
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