Review Article

Chinese Herbal Medicine Alleviates Myocardial Ischemia/Reperfusion Injury by Regulating Endoplasmic Reticulum Stress

Table 2

The role of patented drugs from Chinese herbs in the regulation of ER stress in myocardial I/R.

Patented drugsExperimental modelsEffectsMechanismsReferences

Qishen granuleOGD/R in H9c2 cellsApoptosis↓, ER stress↓Bcl-2/BAX↑, caspases-3/12↓, IRE1-CryAB↑[161]
Shuxuening injectionI/R injury in ratsOxidative damage↓, inflammation↓, ER stress↓CK↓, LDH↓, cTnI↓, MDA↓, SOD↑, GSH-Px↑, CAT↑, GRP78↓, CRT↓, CHOP↓, caspase-12↓, TLR4/NF-κB↓[162]