Anti-Inflammatory Effects of Heat-Processed <i>Artemisia capillaris</i> Thunberg by Regulating I<i>κ</i>B<i>α</i>/NF-<i>κ</i>B Complex and 15-PGDH in Mouse Macrophage Cells

<div>Effects of HPAC on cell viability and cytokine production. (a) RAW 264.7 cells were treated with 5–500 <i>μ</i>g/mL of HPAC and cell viability was determined by MTT assay. RAW 264.7 cells pretreated with indicated concentration of HPAC followed by LPS for 24 h and the production of (b) IL-6, (c) IL-1<i>β,</i> and (d) TNF-<i>α</i> were determined by ELISA. DXM was used as a positive control. The data are presented as means ± SEM (<i>n</i> = 3). 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602Z"></path></g><g transform="matrix(.013,0,0,-0.013,46.086,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,49.05,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,55.29,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,61.53,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> versus LPS group.</div>

Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Anti-Inflammatory Effects of Heat-Processed <i>Artemisia capillaris</i> Thunberg by Regulating I<i>κ</i>B<i>α</i>/NF-<i>κ</i>B Complex and 15-PGDH in Mouse Macrophage Cells 

Figure 2 | Anti-Inflammatory Effects of Heat-Processed Artemisia capillaris Thunberg by Regulating IκBα/NF-κB Complex and 15-PGDH in Mouse Macrophage Cells 