The Relationships between Leptin, Genotype, and Chinese Medicine Body Constitution for Obesity

Table 5

Comparisons of genomic profiles within 3 traditional Chinese medicine body constitutions (TCMBC).

Parameters			Yang deficiency (YangDC)			Yin deficiency (YinDC)			Phlegm-stasis (PSC)
			(+) n = 29	(−) n = 21		(+) n = 33	(−) n = 17		(+) n = 29	(−) n = 21
Obesity polymorphisms
ADRB2 (starch)	rs1042713	Low	11 (37.9%)	5 (23.8%)	0.50	13 (39.4%)	3 (17.6%)	0.20	9 (31.0%)	7 (33.3%)	0.79
		Medium	12 (41.4%)	12 (57.1%)		13 (39.4%)	11(64.7%)		15 (51.7%)	9 (42.9%)
		High	6 (20.7%)	4 (19.0%)		7 (21.2%)	3 (17.6%)		5 (17.2%)	5 (23.8%)
	rs1042714	Low	27 (93.1%)	19 (90.5%)	0.74	31 (93.9%)	15 (88.2%)	0.48	27 (93.1%)	19 (90.5%)	0.74
		Medium	2 (6.9%)	2 (9.5%)		2 (6.1%)	2 (11.8%)		2 (6.9%)	2 (9.5%)
		Low	1 (3.4%)	0 (0.0%)	0.091	1 (3.0%)	0 (0.0%)	0.15	1 (3.4%)	0 (0.0%)	0.63
ADRB3 (visceral)	rs4994	Medium	2 (6.9%)	6 (28.6%)		3 (9.1%)	5 (29.4%)		4 (13.8%)	4 (19.0%)
		High	26 (89.7%)	15 (71.4%)		29 (87.9%)	12 (70.6%)		24 (82.8%)	17 (81.0%)
		Low	3 (10.3%)	3 (14.3%)	0.70	3 (9.1%)	3 (17.6%)	0.46	2 (6.9%)	4 (19.0%)	0.42
GNB3 (metabolism)	rs5443	Medium	13 (44.8%)	11 (52.4%)		15 (45.5%)	9 (52.9%)		15 (51.7%)	9 (42.9%)
		High	13 (44.8%)	7 (33.3%)		15 (45.5%)	5 (29.4%)		12 (41.4%)	8 (38.1%)
UCP1 (stubborn)	rs1800592	Low	3 (10.3%)	5 (23.8%)	0.18	4 (12.1%)	4 (23.5%)	0.45	5 (17.2%)	3 (14.3%)	0.052
		Medium	16 (55.2%)	13 (61.9%)		19 (57.6%)	10 (58.8%)		13 (44.8%)	16 (76.2%)
		High	10 (34.5%)	3 (14.3%)		10 (30.3%)	3 (17.6%)		11 (37.9%)	2 (9.5%)
FTO (appetite)	rs9939609	Low	20 (69.0%)	15 (71.4%)	0.46	24 (72.7%)	11 (64.7%)	0.37	20 (69.0%)	15 (71.4%)	0.46
		Medium	7 (24.1%)	6 (28.6%)		7 (21.2%)	6 (35.3%)		7 (24.1%)	6 (28.6%)
		High	2 (6.9%)	0 (0.0%)		2 (6.1%)	0 (0.0%)		2 (6.9%)	0 (0.0%)