Research Article

LianXia Formula Granule Attenuates Cardiac Sympathetic Remodeling in Rats with Myocardial Infarction via the NGF/TrKA/PI3K/AKT Signaling Pathway

Figure 6

LianXia Formula Granule alleviates arrhythmia in rats with myocardial infarction via the NGF/TrKA/PI3K/AKT signaling pathway. LianXia Formula Granule treatment downregulated the expression of key molecular proteins and mRNA of NGF/TrKA/PI3K/AKT signaling pathway as well as P-Bad; attenuated sympathetic remodeling in the infarcted border zone of rat cardiac tissues. LXFG, LianXia Formula Granule; NGF, nerve growth factor; TrKA, tyrosine kinase receptor A; PI3K, phosphatidylinositol 3-kinase; AKT, protein kinase B.