Shen Shuai II Recipe Attenuates Renal Interstitial Fibrosis by Improving Hypoxia via the IL-1β/c-Myc Pathway

Figure 5

Shen Shuai II Recipe (SSR) inhibits the interleukin- (IL-) 1β/c-Myc pathway in NRK-49F cells. (a) Effect of SSR on the viability of NRK-49F cells (n = 5). (b) Representative western blotting band of c-Myc protein in NRK-49F cells and c-Myc/β-actin ratio (n = 4). (c) Representative western blotting band of c-Myc, fibronectin (FN), proliferating cell nuclear antigen (PCNA), and collagen- (COL-) III proteins in NRK-49F cells and target protein/β-actin ratios, including c-Myc/β-actin, FN/β-actin, COL-III/β-actin, and PCNA/β-actin ratios (n = 4). Values are mean ± SE.

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