Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling

Figure 1

Fraxetin inhibits the proliferation of the U251 cells. (a) RTCA assay. Cells were treated with fraxetin (0 μM, 100 μM, and 200 μM), and cell index was automatically recorded every 15 min. (b) CCK-8 assay. Cells were treated with fraxetin (0 μM, 100 μM, and 200 μM) for 24 h. ((c) and (d)) Colony formation assay. Cells were treated with fraxetin (0 μM, 100 μM, and 200 μM) for 14 days. ((e) and (f)) Western blot analysis of Ki67 protein in U251 cells treated with fraxetin (0 μM, 100 μM, and 200 μM). ; .

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