Antidepressant and Anxiolytic Effects and Subacute Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models

Table 3

Average organ weight index of the Sprague-Dawley rats aged 12–14 weeks.

Parameter	Control	PAE 100 mg/kg	PAE 300 (mg/kg)	PAE 1000 mg/kg
Heart	0.0034 ± 0.0002	0.0027 ± 0.0002	0.0036 ± 0.0002	0.0032 ± 0.0002
Liver	0.0269 ± 0.0011	0.0227 ± 0.0015	0.0300 ± 0.0016	0.0262 ± 0.0012
Spleen	0.0031 ± 0.0001	0.0032 ± 0.0005	0.0040 ± 0.0004	0.0035 ± 0.0003
Left kidney	0.0026 ± 0.0002	0.0023 ± 0.0001	0.0027 ± 0.0002	0.0026 ± 0.0002
Right kidney	0.0027 ± 0.0001	0.0023 ± 0.0002	0.0030 ± 0.0002	0.0026 ± 0.0002
Lungs	0.0079 ± 0.0007	0.0060 ± 0.0001	0.0077 ± 0.0004	0.0062 ± 0.0006
Brain	0.0072 ± 0.0002	0.0074 ± 0.0001	0.0072 ± 0.0003	0.0074 ± 0.0001

Organ weight index = organ weight/carcass weight. Results are presented as mean ± SEM (n = 5). One-way analysis of variance of all the datasets revealed no statistical significance ().