Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-<i>β</i>1/Smad Signaling Pathway Inhibition

<div>Effects of QC on cardiac oxidative stress injury and Ang-II content after TAC surgery in mice. (a) IHC-stained sections of 8-OHdG; scale bar, 50 <i>μ</i>m. (b) Quantification of 8-OHdG-positive cells in indicated groups. 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Data are presented as mean ± SEM and <i>n</i> = 5.</div>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-<i>β</i>1/Smad Signaling Pathway Inhibition 

Figure 4 | Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-β1/Smad Signaling Pathway Inhibition 