Research Article

Aboriginal Bacterial Flora in the Uricase-Deficient Rat Gut is Not the Main Factor Affecting Serum Uric Acid

Figure 2

Food and water intake and urine and stool output of the male Uox-/- rats treated with antibiotics for 5 days (mean + SD, n = 6). There were no significant differences between day 0 and day 5 in food (a) and water (b) consumption in 24 h. There was no difference between day 0 and day 5 in the volume of 24 h urine (c) either. However, in day 5, the rats excreted more amount of stool (d). Day 0, the day before treatment; day 5, treated with ampicillin (90 mg/kg) and ciprofloxacin (150 mg/kg) for 5 days. vs. day 0, paired-sample t-test.