Research Article

miR-16-5p Regulates PTPN4 and Affects Cardiomyocyte Apoptosis and Autophagy Induced by Hypoxia/Reoxygenation

Figure 4

Silencing PTPN4 reverses the inhibitory effect of knockdown of miR-16-5p on H/R-induced AC16 cell damage: (a) PYPN4 protein in AC16 cells; (b) LDH levels in AC16 cells; (c) CK-MB levels in AC16 cells; (d) AC16 cell apoptosis level; (e) autophagy-related protein levels in AC16 cells. , , and vs. the NC group; and vs. the sh-NC + H/R group; , , and vs. the miR-16-5p inhibitor + H/R group.
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