Exploring the Mechanisms of Arsenic Trioxide (Pishuang) in Hepatocellular Carcinoma Based on Network Pharmacology

Table 2

Network topology analysis of pathways.

No.	Entry ID	Pathway	Degree	Average shortest path length	Closeness centrality	Neighborhood connectivity	Radiality
1	hsa04151	PI3K-Akt signaling pathway	16	2.317	0.432	5.125	0.671
2	hsa04370	VEGF signaling pathway	6	2.635	0.380	6.167	0.591
3	hsa04115	p53 signaling pathway	6	2.762	0.362	4.667	0.560
4	hsa04066	HIF-1 signaling pathway	6	2.667	0.375	6.000	0.583
5	hsa04668	TNF signaling pathway	6	2.635	0.380	5.500	0.591
6	hsa04152	AMPK signaling pathway	6	2.698	0.371	4.833	0.575
7	hsa04010	MAPK signaling pathway	6	2.635	0.380	6.500	0.591
8	hsa04064	NF-kappa B signaling pathway	5	2.794	0.358	4.800	0.552
9	hsa04068	FoxO signaling pathway	5	2.698	0.371	6.200	0.575
10	hsa04012	ErbB signaling pathway	4	2.762	0.362	6.750	0.560