Research Article
Paeoniflorin Improved Constipation in the Loperamide-Induced Rat Model via TGR5/TRPA1 Signaling-Mediated 5-Hydroxytryptamine Secretion
Figure 2
Paeoniflorin triggered 5-HT secretion and Tph-1 expression for gut motility. (a) The 5-HT secretion in the serum of rats was assessed using ELISA. (b–d) The expression of Tph-1 in colonic tissues of rats was tested using western blot and immunofluorescence (IF) stain. Scale 100 μm. Data are mean ± SEM. vs. NC group, and vs. model group.
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