Production of an Animal Model of Semi-Yin and Semi-Yang Syndrome with Diabetic Ulcers and Study of Its Pathological and Metabolic Features

Table 1

Quantitative scale for traditional Chinese medicine (TCM) syndromes in diabetic ulcer rats.

Site	Symptoms		1	2	3	4	Weighting coefficient
Local wound	Pus	Amount	Small	Moderate	Large	Huge	0.5
		Color	Clear	Yellowish white	Yellowish cloudy	Cloudy/greenish black	1
		Condition	Thick	Less thick	Clear	Watery	1
		Odor	Fishy	Less stinky	Stinky	Blister	0.5
	Slough	Amount	Small	Moderate	Large	Huge	1
		Cast off	Cast off easily from the skin upon pulling	Attached closely	Reoccurrence after treatment	Dry	0.5
	Granulation tissue	Color	Ruddy, soft, and well-developed	Well-developed	Poorly developed	Small amount and greyish white	1
		Granulation particles	Difference in size	Large in size	Swelling	No	0.5
	Epithelial growth		Large area	Large	Moderate	Small	0.5
Physical condition	Color of fur		White and shiny	White and less shiny	Yellowish white and dull	Pale yellow, dull, and fur loss	0.5
	Food		15 g/200 g ≤ and <30 g	30 g/200 g≤ and <35 g/200 g	35 g/200 g ≤ and <45 g/200 g	<20 g/200 g	0.5
	Water		40 mL/200 g ≤ and <100 mL/200 g	100 mL/200 g≤ and 140 mL/200 g	140 mL/200 g ≤ and <150 mL/200 g	>150 mL/200 g	0.5
	Activity		High	Low	Lethargically curling up	Tired and faint	0.5
	Quality of sleep		Well	Moderate	Poor	Sleepiness	0.5
	Excrement (condition)		Normal	Sticky	Watery	Dry	0.5
	Urine (amount)		Normal	A bit more	More	Less	0.5

Note. Yang syndrome ≤ 15; 15 < semi-Yin and semi-Yang (SYSY) syndrome ≤ 30; 30 < Yin syndrome ≤ 40; if the value is closer to 22, it indicates that the symptoms are more in line with those of SYSY syndrome.