Genetic Toxicology and Safety Pharmacological Evaluation of Forsythin

Table 2

Results of the chromosomal aberrations test for forsythin.

Group	Dosage (µg/ml)	Number of cells scored	No. of cells with aberrations
			−S9		+S9
			24 h	48 h	6–18 h
DMSO^a	—	200	4.0	2.5	2.0
Mitomycin C^b	0.25	200	14.5	18.5
Cyclophosphamide^b	20	200			19.0
Forsythin	125	200	5.0	2.5	5.0
	250	200	4.5	1.5	5.0
	500	200	5.0	5.0	4.5

^aNegative control. ^bPositive control. , compared with the negative control group. , compared with the negative control group.