Research Article
Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl3 and Aqueous Extracts of Ficus palmata
Figure 5
Effects of (Fp.Aq) extract on ethanol-mediated stomach histopathologic changes. Stomach tissues (n = 5) from each experimental group were processed for histological evaluation at 1 h after ethanol challenge. (A) Histological changes of apoptotic markers (TNF-α, P-NFκB, and COX-2) in the stomach, scale bar = 20 μm, magnification 40X in the control group, ethanol group, Fp.Aq extract group, and standard omeprazole group. (B, C) Severity scores of stomach injury in different groups (n = 5) calculated via relative density of value (A.U.) and relative integrated density. Data were analyzed by two-way ANOVA followed by post hoc Tukey’s test using GraphPad Prism software in mean ± SEM. vs. ethanol group and vs. ethanol group. (D) Histopathological examination of the saline group, ethanol group, test group, and omeprazole group.
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