Research Article

Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl3 and Aqueous Extracts of Ficus palmata

Table 3

Protective effect of Ficus palmata extracts: chloroform (Fp.CHCl3), aqueous (Fp.Aq), and omeprazole against ethanol-induced gastric ulcers in rats.

TreatmentUlcer index% Inhibition

Saline 10 mL/kg + ethanol10.0 ± 0.0-
Fp.CHCl3 (50 mg/kg) + ethanol7.8 ± 0.3720.40
Fp.CHCl3(100 mg/kg) + ethanol4.4 ± 0.2455.10
Fp.CHCl3 (300 mg/kg) + ethanol2.4 ± 0.2475.51
Fp.Aq (50 mg/kg) + ethanol6.2 ± 0.3735.41
Fp.Aq (100 mg/kg) + ethanol4.4 ± 0.2454.16
Fp.Aq (300 mg/kg) + ethanol2.4 ± 0.2475
Omeprazole (20 mg/kg) + ethanol1.4 ± 0.2486

vs. control saline group, one-way analysis of variance followed by post hoc Tukey’s test, n = 5.