Biological Activities and Chemistry of Triterpene Saponins from Medicago Species: An Update Review

Table 5

Saponins from M. sativa.

Aglycone	No.	3-OH substituted	28-COOH substituted	Formula weight	Ref.
Medicagenic acid	49	β-D-GlcA	α-L-Rha(1⟶2)-α-L-Ara	C47H72O20 956	[30]
	50	α-L-Rha(1⟶2)-β-D-Gal(1⟶2)-β-D-GluA	—	C48H74O21 986	[31]
	51	β-D-GlcA	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C52H80O24 1088	[18, 31]
	52	β-D-GlcA	β-D-GlcA	C42H62O18 854	[32]
	53	β-D-Glc(1⟶3)-β-D-Glc	α-L-Rha(1⟶2)-α-L-Ara	C53H84O24 1104	[32]
	54	β-D-GlcA	β-D-Api(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C57H88O28 1220	[32]
	55	β-D-Glc	β-D-Glc(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C53H84O24 1104	[33]
	56	β-D-Glc(1⟶2)-β-D-Glc	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C58H92O28 1236	[18, 33]
	57	α-L-Ara(1⟶2)-β-D-Glc(1⟶2)-α-L-Ara	β-D-Glc	C52H82O24 1090	[33]
	58	β-D-Glc	—	C36H56O11 664	[1, 18, 25]
	59	β-D-Glc	β-D-Glc	C42H66O16 826	[1, 18, 25, 34]
	60	β-D-Glc	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C52H82O23 1074	[1, 6, 18]
	61	β-D-Glc(1⟶2)-β-D-Glc	β-D-Glc	C48H76O21 988	[18, 25]
	62	β-D-Glc(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	—	C48H76O21 988	[34]
	63	α-L-Rha(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	—	C48H76O20 972	[34]
Zanhic acid	64	β-D-GlcA	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C52H80O25 1104	[30]
	65	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	—	C46H72O19 928	[32]
	66	β-D-Glc	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C52H82O24 1090	[32]
	67	β-D-Glc(1⟶3)-β-D-Glc	α-L-Rha(1⟶2)-α-L-Ara	C53H84O25 1120	[32]
	68	β-D-Glc	α-L-Ara(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C57H90O28 1222	[32]
	69	β-D-GlcA	α-L-Ara(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C57H88O29 1236	[32]
	70	β-D-Glc(1⟶3)-β-D-Glc	α-L-Ara(1⟶3)-α-L-Rha(1⟶2)-α-L-Ara	C58H92O29 1252	[32]
	71	β-D-Glc(1⟶2)-β-D-Glc	α-L-Ara(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C63H100O33 1384	[32]
	72	α-L-Ara(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	β-D-Api(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C68H108O37 1516	[32]
	73	β-D-Glc(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C64H102O34 1414	[1, 18, 25]
	74	β-D-Glc(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	β-D-Api(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C69H110O38 1546	[18, 30]
	75	β-D-GluA	α-L-Ara(1⟶3)-[β-D-Xyl(1⟶4)]-α-L-Rha(1⟶2)-α-L-Ara	C57H88O29 1236	[1]
Bayogenin	76	α-L-Ara	β-D-Glc	C41H66O14 782	[32]
	77^∗	β-D-Gal(1⟶2)-β-D-GluAME	β-D-Glu	C49H76O22 1016	[35]
	78^∗	β-D-Xyl(1⟶4)-β-D-GluAME	β-D-Glc	C48H76O20 972	[35]
Hederagenin	79	—	β-D-Glc	C36H58O9 634	[32]
	80	α-L-Ara(1⟶2)-β-D-Glc	β-D-Glc	C47H76O18 928	[18]
	81	α-L-Ara(1⟶2)-β-D-Glc(1⟶2)-α-L-Ara	—	C46H74O17 898	[18]
	82	β-D-Glc(1⟶2)-α-L-Ara	—	C41H66O13 766	[1]
	83	α-L-Ara(1⟶2)-β-D-Glc(1⟶2)-α-L-Ara	β-D-Glc	C52H84O22 1060	[18, 34]
	84^∗	β-D-Xyl(1⟶3)-β-D-Glc	β-D-Xyl(1⟶4)-α-L-Rha(1⟶2)-α-L-Ara	C57H92O25 1176	[34]
	85^∗	α-L-Ara(1⟶2)-β-D-Glc(1⟶2)-β-D-Xyl	β-D-Glc	C52H84O22 1060	[34]
	86^∗	β-D-Xyl(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	β-D-Glc	C53H86O23 1090	[34]
	87^∗	β-D-Glc(1⟶2)-β-D-Glc(1⟶2)-α-L-Ara	β-D-Glc	C53H86O23 1090	[34]
	88^∗	α-L-Ara(1⟶2)-β-D-Glc(1⟶2)-β-D-GluAME	β-D-Glc	C54H86O24 1118	[35]
	89	β-D-Glc(1⟶2)-α-L-Ara	β-D-Glc	C47H76O18 928	[34]
2β,3β-Dihydroxy-23-oxo-olean-12en-28oic acid	90	β-D-GlcA	β-D-Glc	C42H64O16 824	[32]
	91^∗	β-D-Xyl(1⟶2)-β-D-Glc(1⟶2)-β-D-Glc	β-D-Glc	C53H84O24 1104	[34]
Soyasapogenol B	92	α-L-Rha(1⟶2)-β-D-Gal(1⟶2)-β-D-GluA	—	C48H78O18 942	[1, 18, 25, 33, 34]