Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF- and PI3K/AKT Pathways

Figure 10

Inhibition of MMP-1, MMP-3, MMP-13, and TIMP4 mRNA expression in IL-1β-induced SW1353 cells by si-AKT and si-NF-. The data are derived from three independent experiments and expressed as the mean ± standard deviation ( < 0.01 compared with the control group; ^# < 0.05 compared with the IL-1β-treated group).

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