Research Article

Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF- and PI3K/AKT Pathways

Figure 3

Mankin’s scoring was based on the hematoxylin-eosin (HE) staining results. (a) Blank control group; (b) OA model group (established with the Hulth method); (c) TFRD-treated group (treated with total flavonoids of Rhizoma Drynariae (TFRD) after model induction with the Hulth method. The data are expressed as the mean ± standard deviation ( < 0.01 compared with Group a; # < 0.01 compared with Group b).