Review Article
Meta-Analysis of Clinical Efficacy and Safety of Tripterygium wilfordii Polyglycosides Tablets in the Treatment of Chronic Kidney Disease
Table 2
Results of meta-analysis of clinical efficacy.
| | Subgroup analysis | No. of studies | Weighted combination | Heterogeneity | Egger’s bias value | Metaregression
value | | OR [95% conf. interval] | value | I2 | value |
| | Disease type | | NS | 31 | 3.337 (2.649, 4.203) | | 22.7% | | | | | RNS | 14 | 4.141 (3.037, 5.646) | | 0.0% | | | | PNS | 17 | 2.822 (2.109, 3.776) | | 0.0% | | | | MN | 3 | 4.761 (2.182, 10.385) | | 0.0% | | | | IgAN | 1 | 4.000 (1.129, 14.175) | | — | — | — |
| | Mode of medication | | Single drug | 6 | 4.037 (2.241, 7.272) | | 0.0% | | | | | Combined use of drugs | 60 | 3.373 (2.882, 3.947) | | 0.0% | | |
| | Course of treatment | | <6 months | 20 | 3.705 (2.854, 4.809) | | 0.0% | | | | | ≥6 months | 28 | 3.318 (2.622, 4.198) | | 0.0% | | | | ≥12 months | 17 | 3.104 (2.272, 4.240) | | 26.6% | | |
| | Age of the patient (year) | | 0–18 | 2 | 4.981 (2.006, 12.365) | | 0.0% | | — | | | 19–65 | 45 | 3.591 (2.974, 4.337) | | 0.0% | | | | >66 | 18 | 3.454 (2.606, 4.577) | | 0.0% | | | | Not reported | 1 | 0.167 (0.034, 0.805) | | — | — | — | — | | Total | 66 | 3.415 (2.933, 3.975) | | 0.0% | | | — |
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