Ginsenoside Rb3 Alleviates the Toxic Effect of Cisplatin on the Kidney during Its Treatment to Oral Cancer via TGF-β-Mediated Mitochondrial Apoptosis

Figure 5

Rb3 suppressed CPT-evoked mitochondrial apoptosis in GP-293 cells. (a) Flow cytometry of JC-1 staining for mitochondrial membrane potential change. (b) Quantitative analysis for mitochondrial membrane potential change. (c) Western blotting for the expression levels of Bax and Bcl-2. (d) Quantitative analysis of densitometry for the expression of Bax and Bcl-2.  < 0.01 and  < 0.001 compared to the control group; ^# < 0.05 and ^## < 0.01 compared to the CPT group.

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