Hirudo Lyophilized Powder Ameliorates Renal Injury in Diabetic Rats by Suppressing Oxidative Stress and Inflammation
Effects of Hirudo lyophilized powder on renal histopathology of diabetic rats. The SL, SM, and SH group rats were dosed by oral gavage once daily for 16 weeks with Hirudo lyophilized powder. The C and DM group rats were administered the same volume of vehicle used to prepare the test medications. (a) Pathological morphology of renal tissues in each group rats (×400); scale bar, 50 m. (b) The fibrosis area of renal tissues in each group rats. Data are presented as means ± SD; < 0.01 vs. C group; # < 0.05 and ## < 0.01 vs. DM group.