Evaluation of the Antimalarial Activity of the Leaf Latex of Aloe weloensis (Aloaceae) against Plasmodium Parasites

Table 4

Parasitemia level, % suppression, and survival time of infected mice treated by the leaf latex of Aloe weloensis in the prophylactic test.

Group	% parasitemia	%suppression	Survival time (days)
10 ml/kg NC	65.31 ± 0.17	—	5.72 ± 0.42
25 mg/kg CQ	00.0 ± 00^a3b2	100	30.45 ± 0.18^a3b2
200 mg/kg LL	27.42 ± 0.23^a1c1d1e2	37.87	8.21 ± 0.15^a1d1e2
400 mg/kg LL	16.52 ± 0.18^a2b1	46.29	14.10 ± 0.31^a2
600 mg/kg LL	12.12 ± 0.41^a2b1	56.68	17.50 ± 0.22^a3b1

Data are expressed as means ± standard error of the mean; n = 6. ^aCompared to vehicle; ^bcompared to 200 mg/kg; ^ccompared to 400 mg/kg; ^dcompared to 600 mg/kg; ^ecompared to 25 mg/kg CQ. ¹, ², and ³ with respect to vehicle control. CQ, chloroquine; LL, leaf latex; NC, negative control.