Research Article

Efficacy of Oral Administration of Allium sativum Powder “Garlic Extract” on Lipid Profile, Inflammation, and Cardiovascular Indices among Hemodialysis Patients

Table 2

Randomized crossover, double-blind, and placebo-controlled trials investigating the oral effect administration of Allium sativum powder on lipid profile, inflammation, and cardiovascular indexes.

Baseline effectCarryover effect: drug-placebo vs. placebo-drugPeriod effect: period 1 vs. period 2Treatment effect: drug vs. placebo
Est. (SE)dfEst.(SE)dfEst.(SE)dfEst.(SE)df

K0.30 (0.06)67<0.001−0.08 (0.10)680.429−0.06 (0.08)670.479−0.04 (0.08)670.630
BUN0.62 (0.06)67<0.001−5.07 (2.44)680.04111.32 (2.22)67<0.0010.52 (2.21)670.814
Cr0.05 (0.02)660.018−0.79 (0.75)680.3020.33 (0.28)660.2480.58 (0.28)660.047
Ca0.55 (0.08)58<0.0010.19 (0.13)680.134−0.60 (0.08)58<0.0010.02 (0.08)580.857
Ph0.74 (0.06)67<0.001−0.43 (0.15)680.007−0.57 (0.17)680.001−0.30 (0.16)670.068
Chol0.93 (0.04)67<0.001−4.44 (2.52)680.082−16.28 (2.72)67<0.001−2.66 (2.71)670.329
TG0.88 (0.03)67<0.0011.01 (5.44)680.86412.17 (7.62)670.115−16.21 (7.60)670.037
Na0.06 (0.06)670.3060.36 (0.64)680.573−0.26 (0.68)670.708−0.66 (0.49)670.177
OXLDL0.19 (0.05)67<0.001−36.96 (61.83)680.552−66.85 (57.14)670.246−325.27 (44.35)67<0.001
TAC0.49 (0.06)67<0.001−0.15 (0.07)680.0430.09 (0.12)670.4610.21 (0.11)660.077
HCY0.63 (0.05)67<0.0011.94 (1.29)680.135−2.05 (1.32)670.127−7.29 (1.33)67<0.001

k: kalium; BUN: blood urea nitrogen; Cr: creatinine; Ca: calcium; Ph: the power of hydrogen; Chol: cholesterol; TG: triglyceride; Na: natrium; OXLDL: oxidized low-density lipoprotein; TAC: total antioxidant capacity; HCY: homocysteine.