Efficacy of Oral Administration of Allium sativum Powder “Garlic Extract” on Lipid Profile, Inflammation, and Cardiovascular Indices among Hemodialysis Patients
Table 2
Randomized crossover, double-blind, and placebo-controlled trials investigating the oral effect administration of Allium sativum powder on lipid profile, inflammation, and cardiovascular indexes.
Baseline effect
Carryover effect: drug-placebo vs. placebo-drug
Period effect: period 1 vs. period 2
Treatment effect: drug vs. placebo
Est. (SE)
df
Est.(SE)
df
Est.(SE)
df
Est.(SE)
df
K
0.30 (0.06)
67
<0.001
−0.08 (0.10)
68
0.429
−0.06 (0.08)
67
0.479
−0.04 (0.08)
67
0.630
BUN
0.62 (0.06)
67
<0.001
−5.07 (2.44)
68
0.041
11.32 (2.22)
67
<0.001
0.52 (2.21)
67
0.814
Cr
0.05 (0.02)
66
0.018
−0.79 (0.75)
68
0.302
0.33 (0.28)
66
0.248
0.58 (0.28)
66
0.047
Ca
0.55 (0.08)
58
<0.001
0.19 (0.13)
68
0.134
−0.60 (0.08)
58
<0.001
0.02 (0.08)
58
0.857
Ph
0.74 (0.06)
67
<0.001
−0.43 (0.15)
68
0.007
−0.57 (0.17)
68
0.001
−0.30 (0.16)
67
0.068
Chol
0.93 (0.04)
67
<0.001
−4.44 (2.52)
68
0.082
−16.28 (2.72)
67
<0.001
−2.66 (2.71)
67
0.329
TG
0.88 (0.03)
67
<0.001
1.01 (5.44)
68
0.864
12.17 (7.62)
67
0.115
−16.21 (7.60)
67
0.037
Na
0.06 (0.06)
67
0.306
0.36 (0.64)
68
0.573
−0.26 (0.68)
67
0.708
−0.66 (0.49)
67
0.177
OXLDL
0.19 (0.05)
67
<0.001
−36.96 (61.83)
68
0.552
−66.85 (57.14)
67
0.246
−325.27 (44.35)
67
<0.001
TAC
0.49 (0.06)
67
<0.001
−0.15 (0.07)
68
0.043
0.09 (0.12)
67
0.461
0.21 (0.11)
66
0.077
HCY
0.63 (0.05)
67
<0.001
1.94 (1.29)
68
0.135
−2.05 (1.32)
67
0.127
−7.29 (1.33)
67
<0.001
k: kalium; BUN: blood urea nitrogen; Cr: creatinine; Ca: calcium; Ph: the power of hydrogen; Chol: cholesterol; TG: triglyceride; Na: natrium; OXLDL: oxidized low-density lipoprotein; TAC: total antioxidant capacity; HCY: homocysteine.