Research Article

Tongxie Anchang Decoction Relieves Visceral Hypersensitivity in Diarrhea-Predominant Irritable Bowel Syndrome Rats by Regulating the NGF/TrkA Signaling Pathway

Table 3

Effect of TXACD on AWR score in rats.

Groupn20 mmHg40 mmHg60 mmHg80 mmHg

NH60.56 ± 0.271.39 ± 0.251.89 ± 0.402.56 ± 0.46
NR61.22 ± 0.342.56 ± 0.343.39 ± 0.393.89 ± 0.40
Low-dose61.11 ± 0.402.22 ± 0.543.28 ± 0.253.83 ± 0.62
Middle dose61.06 ± 0.441.67 ± 0.30##2.28 ± 0.25##2.94 ± 0.49##
High dose61.11 ± 0.401.67 ± 0.37##2.72 ± 0.39##3.17 ± 0.46##
Pinaverium bromide (PB)61.06 ± 0.391.61 ± 0.25##2.06 ± 0.44##2.72 ± 0.39##

 < 0.01 versus the normal control (no handling (NH)) group.  < 0.01 versus the neonatal maternal separation (NMS) + restraint stress (RS) (NR) group.