Research Article
Tongxie Anchang Decoction Relieves Visceral Hypersensitivity in Diarrhea-Predominant Irritable Bowel Syndrome Rats by Regulating the NGF/TrkA Signaling Pathway
Table 3
Effect of TXACD on AWR score in rats.
| Group | n | 20 mmHg | 40 mmHg | 60 mmHg | 80 mmHg |
| NH | 6 | 0.56 ± 0.27 | 1.39 ± 0.25 | 1.89 ± 0.40 | 2.56 ± 0.46 | NR | 6 | 1.22 ± 0.34 | 2.56 ± 0.34 | 3.39 ± 0.39 | 3.89 ± 0.40 | Low-dose | 6 | 1.11 ± 0.40 | 2.22 ± 0.54 | 3.28 ± 0.25 | 3.83 ± 0.62 | Middle dose | 6 | 1.06 ± 0.44 | 1.67 ± 0.30## | 2.28 ± 0.25## | 2.94 ± 0.49## | High dose | 6 | 1.11 ± 0.40 | 1.67 ± 0.37## | 2.72 ± 0.39## | 3.17 ± 0.46## | Pinaverium bromide (PB) | 6 | 1.06 ± 0.39 | 1.61 ± 0.25## | 2.06 ± 0.44## | 2.72 ± 0.39## |
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< 0.01 versus the normal control (no handling (NH)) group. < 0.01 versus the neonatal maternal separation (NMS) + restraint stress (RS) (NR) group. |