Effect of 70% Ethanol Extract and its Solvent Fractions of Artemisia afra (Jacq. Ex Willd.) against Pentylenetetrazole-Induced Seizure in Mice

Figure 4

Mean duration of convulsion with 1000 mg/kg solvent fraction of hydroethanolic A. afra crude extract 30 min before subcutaneous PTZ administration for the positive (diazepam 2 mg/kg) and negative (physiological saline 10 mg/kg) control groups (n = 6 for each group). Values represent mean ± SEM of three independent experiments (n = 6 for each group). SEM = standard error of the mean, AaFw = A. afra water fraction, AaFe = A. afra ethanol fraction, AaFd = A. afra dichloromethane fraction, AaFp = A. afra petroleum ether fraction, DZP = diazepam, and Ctrl = control.