Research Article
Improvement of Total Flavonoids from Dracocephalum moldavica L. in Rats with Chronic Mountain Sickness through 1H-NMR Metabonomics
Table 2
Serum endogenous merabolite attribution and chemical shift.
| | No | Metabolite | Chemical shift (ppm) | Assignment |
| | 1 | Lipid （LDL/VLDL) | 0.85 (m), 1.25 (m), 2.74 (m) | C26 and C27, （CH2）n, C＝CCH2C＝C | | 2 | Isoleucine | 0.93 (t)， 1.00 (d) | δ-CH3, β-CH3 | | 3 | Leucine | 0.97 (d) | δ-CH3 | | 4 | Valine | 1.02 (d), 3.57 (d) | γ-CH3， α-CH2 | | 5 | 3-Hydroxybutyrate | 1.20 (d)， 2.31 (m) | γ-CH3， halfα-CH2 | | 6 | Lactate | 1.33 (d)， 4.11 (q) | CH3， CH | | 7 | Alanine | 1.46 (d) | CH3 | | 8 | Acetate | 1.91 (s), 2.22 (s) | CH3 | | 9 | Glycoprotein | 2.04 (s）, 2.14 (s) | NHCOCH3 | | 10 | Acetoacetate | 2.27 (s) | CH3 | | 11 | Pyruvate | 2.36 (s) | CH3 | | 12 | Glutamine | 2.41 (m) | halfγ-CH3 | | 13 | Citrate | 2.52 (d), 2.66 (d) | Half-CH2 | | 14 | Creatine | 3.03 (s), 3.93 (s) | CH3,CH2 | | 15 | Choline | 3.21 (s) | N(CH3)O3 | | 16 | Taurine | 3.42 (t) | CH2SO3 | | 17 | Proline | 3.45 (m) | Halfδ-CH2 | | 18 | Glycine | 3.54 (s) | CH2 | | 19 | Citrulline | 3.70 (m) | α-CH2 | | 20 | Alpha-glucose | 3.54 (dd), 3.84 (m), 5.23 (d) | H2, halfδ-CH2-C6, H1 |
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1H-NMR metabolism multivariate statistical analysis of the sera of rats in the CMS model group.
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