Research Article

Protective Effect of Opuntia dillenii Haw Fruit against Lead Acetate-Induced Hepatotoxicity: In Vitro and In Vivo Studies

Figure 5

Paraffin sections stained by hematoxylin and eosin (H&E × 20 and ×40) for histopathological examination of liver tissues of rats as follows: normal hepatocytes architecture and sinusoids (HC) and central vein (CV) in the control group ((a) ×20). Alterations in liver tissue including fatty change (FC) ((b) ×40) and hemorrhage (HR) ((c) ×20) as well as the degenerated cells with sinusoidal dilatation (SD) ((d) ×20), cytoplasmic vacuolation (V) ((e) ×40), and pyknotic nuclei (PC) ((f) ×40) in Pb group. Reduction in lead-induced alterations resulted in regeneration of normal sinusoidal structures (SS) ((g) ×40) in the OHAE100 and ((h) ×40) in the OHAE200 groups.