Research Article

Protective Effect of Joa-Gui Em through the Improvement of the NLRP3 and TLR4/NF-κb Signaling by Ischemia/Reperfusion-Induced Acute Renal Failure Rats

Table 2

Effect of JGE on urinalysis for kidney function.

ContARFARF + JGE100ARF + JGE200

UV (ml/day/kg)45.41 ± 2.0670.66 ± 3.28∗∗∗61.31 ± 2.7157.92 ± 1.77
Uosmol (mOsm)2503.8 ± 131.81420.5 ± 86.8∗∗∗1643.1 ± 114.81615.8 ± 62.3
UNaV (mmol/L/Kg)786.75 ± 19.82485.24 ± 30.09∗∗∗566.01 ± 30.92606.73 ± 39.40
UKV (mmol/L/Kg)1556.98 ± 51.95995.33 ± 64.84∗∗∗1302.99 ± 99.761101.53 ± 66.83
UClV (mmol/L/Kg)1324.03 ± 37.16871.52 ± 46.16∗∗∗1044.75 ± 64.87968.47 ± 61.45

Cont, control; ARF, ischemia/reperfusion- (I/R-) induced acute renal failure (ARF) group; ARF + JGE100, JGE 100 mg/kg/day; ARF + JGE200, JGE 200 mg/kg/day for 4 days; UV, urinary volume; Uosmol, urinary osmolality. Values are expressed as mean ± SE. (n = 10). cont∗∗∗ vs. cont.; , vs. ARF.