Research Article

Shu-Di-Huang and Gan-Cao Herb Pair Restored the Differentiation Potentials of Mesenchymal Stem Progenitors in Treating Osteoporosis via Downregulation of NF-κB Signaling Pathway

Figure 1

Network pharmacology analysis of RR-L in treating osteoporosis indicated RR-L involves multiple pathways including inflammation and lipid metabolism. (a) Herb-compounds-targets network construction. (b) Venn analysis revealed 120 shared genes between RR-L and OP. (c) Herb-compounds-OP targets network construction. (d) GO enrichment analysis of 120 shared target genes. (e) KEGG pathway enrichment analysis of 120 shared target genes. (f-g) PPI network and hub gene analysis of 120 shared target genes.
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