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Evidence-Based Complementary and Alternative Medicine
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Evidence-Based Complementary and Alternative Medicine
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2021
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Article
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Tab 2
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Research Article
Phytochemical Analysis Using UPLC-MS/MS Combined with Network Pharmacology Methods to Explore the Biomarkers for the Quality Control of Lingguizhugan Decoction
Table 2
The first 20 key targets of LGZG decoction in treating hyperlipidemias.
No.
Target name
Betweenness centrality
Closeness centrality
Degree
1
TNF
0.1205
0.7204
41
2
AKT1
0.1198
0.7053
40
3
PPARG
0.1057
0.6907
38
4
PPARA
0.0951
0.6569
33
5
IL1B
0.0514
0.6505
32
6
PTGS2
0.0414
0.6091
28
7
RXRA
0.0320
0.6036
24
8
EGFR
0.0230
0.5877
24
9
ACE
0.0371
0.5982
23
10
HMGCR
0.0370
0.5776
20
11
NR3C1
0.0147
0.5492
20
12
ABCA1
0.0240
0.5678
19
13
AGT
0.0320
0.5678
19
14
NR1H3
0.0090
0.5630
18
15
IFNG
0.0144
0.5678
18
16
ESR1
0.0104
0.5194
18
17
REN
0.0139
0.5537
17
18
IL4
0.0105
0.5583
17
19
CETP
0.0142
0.5194
16
20
RXRB
0.0072
0.5276
16