Research Article

Phytochemical Analysis Using UPLC-MS/MS Combined with Network Pharmacology Methods to Explore the Biomarkers for the Quality Control of Lingguizhugan Decoction

Table 2

The first 20 key targets of LGZG decoction in treating hyperlipidemias.

No.Target nameBetweenness centralityCloseness centralityDegree

1TNF0.12050.720441
2AKT10.11980.705340
3PPARG0.10570.690738
4PPARA0.09510.656933
5IL1B0.05140.650532
6PTGS20.04140.609128
7RXRA0.03200.603624
8EGFR0.02300.587724
9ACE0.03710.598223
10HMGCR0.03700.577620
11NR3C10.01470.549220
12ABCA10.02400.567819
13AGT0.03200.567819
14NR1H30.00900.563018
15IFNG0.01440.567818
16ESR10.01040.519418
17REN0.01390.553717
18IL40.01050.558317
19CETP0.01420.519416
20RXRB0.00720.527616