Ameliorative Effects of Pueraria lobata Extract on Postmenopausal Symptoms through Promoting Estrogenic Activity and Bone Markers in Ovariectomized Rats

Table 3

Effects of PE on serotonin and bone turnover markers in OVX rats.

	Serotonin (ng/mL)	CTX-1 (pg/mL)	DYP (nmol/L)	PYD (ng/mL)
Sham	200.10 ± 28.19	167.10 ± 14.10	2.10 ± 0.10	27.07 ± 0.97
OVX	390.20 ± 67.26	155.5 ± 8.14	3.07 ± 0.18	34.92 ± 3.20
PE-25	264.30 ± 38.04	106.80 ± 7.95	2.37 ± 0.07	27.47 ± 1.51
PE-100	205.70 ± 22.92	110.60 ± 7.14	2.23 ± 0.12	25.86 ± 1.42
PE-400	222.60 ± 40.00	104.10 ± 11.25	2.34 ± 0.08	25.18 ± 1.06
PE-1600	159.40 ± 45.05	96.24 ± 9.87	2.09 ± 0.10	25.31 ± 0.88

Data are presented as the mean ± standard error of mean (SEM). Sham, sham operation; OVX, ovariectomy; PE-25, OVX + PE 25 mg/kg; PE-100, OVX + PE 100 mg/kg; PE-400, OVX + PE 400 mg/kg; PE-1600, OVX + PE 1600 mg/kg; CTX-1, C-terminal telopeptide fragment of type I collagen; DYP, deoxypyridinoline; PYD, pyridinoline. and vs. sham group; , , , and vs. OVX group.