Acupotomy Contributes to Suppressing Subchondral Bone Resorption in KOA Rabbits by Regulating the OPG/RANKL Signaling Pathway

Figure 2

Acupotomy intervention inhibited subchondral bone loss in KOA rabbits. (a) (b) HE staining of subchondral bone (magnification × 40). A1: 4w control group, A2: 4w model group, A3: 4w acupotomy group, A4: 4w electroacupuncture group; B1: 6w control group, B2: 6w model group, B3: 6w acupotomy group, B4: 6w electroacupuncture group. (c) Analysis of Tb.Ar in subchondral bone. (d) Analysis of Tb.pm in subchondral bone. (e) Analysis of T.Ar in subchondral bone. (f) Analysis of Tb.N in subchondral bone. (g) Analysis of BV/TV in subchondral bone. (h) Analysis of Tb.Sp in subchondral bone. Values are means ± SEMs. n = 6 per group. Compared with the corresponding control group:  < 0.05 and  < 0.01; compared with the corresponding model group: ^# < 0.05 and ^## < 0.01; compared with the corresponding electroacupuncture group: ^▲ < 0.05 and ^▲▲ < 0.01.

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