A Novel Effective Formulation of Bioactive Compounds for Wound Healing: Preparation, In Vivo Characterization, and Comparison of Various Postbiotics Cold Creams in a Rat Model

Table 3

Wound healing percentages in various days of a 14-day treatment of five rat groups with three postbiotic cold cream formulations, cold cream formulation alone, and no treatment (control).

Rat groups	No treatment (control)	Cold cream alone	L. fermentum cold cream	L. reuteri cold cream	B. S. natto cold cream
Day
2	6.195 ± 0.330	7.800 ± 0.350	7.080 ± 0.600	5.310 ± 0.300	9.734 ± 0.400
3	21.239 ± 1.000	29.203 ± 1.000	30.088 ± 0.900	11.504 ± 0.710	20.354 ± 0.350
4	19.469 ± 0.890	23.009 ± 0.890	46.902 ± 1.210	23.009 ± 1.300	30.088 ± 1.100
5	23.894 ± 0.710	29.203 ± 0.710	46.017 ± 0.840	34.513 ± 2.000	33.628 ± 0.710
7	24.1 ± 0.840	34.513 ± 0.840	52.212 ± 0.840	48.672 ± 1.520	53.982 ± 2.700
8	38.053 ± 0.800	41.593 ± 0.800	60.177 ± 2.550	66.372 ± 0.890	67.256 ± 0.890
10	38.938 ± 1.500	48.672 ± 1.820	76.991 ± 2.170	78.761 ± 0.450	72.566 ± 0.840
11	56.637 ± 1.340	67.257 ± 1.340	76.995 ± 1.300	82.301 ± 0.100	79.646 ± 0.550
13	57.522 ± 3.000	65.487 ± 3.320	84.956 ± 0.550	88.495 ± 0.890	93.805 ± 1.150
14	74.336 ± 4.000	75.221 ± 3.030	91.150 ± 1.000	100.00 ± 0.010	100.00 ± 0.850