Standardized Extract (HemoHIM) Protects against Scopolamine-Induced Amnesia in a Murine Model

Figure 3

The effects of HemoHIM on scopolamine-induced memory impairment in the NORT. (a) Time spent on familiar object (sec), (b) time spent novel object (sec), and (c) Recognition index (%). Ninety minutes before Y-maze, mice were treated with HemoHIM (250 and 500 mg/kg, p.o.) or donepezil (1 mg/kg, p.o.) as a positive control. Memory impairment was induced by scopolamine treatment (1 mg/kg, i.p.). Thirteen different animals were used per group. The data are expressed as the mean ± S.E.M. Significant difference from control group ( < 0.05) and from scopolamine-treated group ( < 0.01).

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