Evidence-Based Complementary and Alternative Medicine / 2021 / Article / Tab 3

Research Article

A Network Pharmacology Approach to Reveal the Underlying Mechanisms of Artemisia annua on the Treatment of Hepatocellular Carcinoma

Table 3

Genes/signaling pathways related with hepatocarcinoma regulated by Artemisia annua.

GOIDSignaling pathwayGroup genes

GO: 0042743Hydrogen peroxide metabolic processCCND1, CYP1A1, EGFR, ESR1, FOS, MMP3, PTGS2
GO: 0060749Mammary gland alveolus developmentAR, CCL2, CCND1, E2F1, EGF, EGFR, ESR1, GSTP1, IGFBP3, MYC
GO: 0071930Negative regulation of transcription involved in G1/S transition of mitotic cell cycleE2F1, RB1
GO: 2001028Positive regulation of endothelial cell chemotaxisHSPB1, MET
GO: 0045742Positive regulation of epidermal growth factor receptor signaling pathwayEGF, MMP9
GO: 0032930Positive regulation of superoxide anion generationCRP, EGFR, GSTP1
GO: 1904705Regulation of vascular smooth muscle cell proliferationGSTP1, MMP2, MMP9