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Evidence-Based Complementary and Alternative Medicine
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Special Issues
Evidence-Based Complementary and Alternative Medicine
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2021
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Article
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Tab 4
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Research Article
Molecular Targets and Mechanisms of
Scutellariae radix
-
Coptidis rhizoma
Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking
Table 4
The main targets of
Scutellariae radix
-
Coptidis rhizoma
drug pair.
Rank
Gene symbol
Gene name
Degree
1
AKT1
RAC-alpha serine/threonine-protein kinase
108
2
TP53
Cellular tumor antigen p53
98
3
IL-6
Interleukin-6
94
4
VEGFA
Vascular endothelial growth factor A
93
5
CASP3
Caspase-3
88
6
JUN
Transcription factor AP-1
86
6
TNF
Tumor necrosis factor
86
8
MYC
Myc proto-oncogene protein
85
9
EGFR
Epidermal growth factor receptor
84
10
PTGS2
Prostaglandin G/H synthase 2
83